Theatre efficiency: confounding factors for surrogate measures

Confounding Factors for Hamilton’s Rule

Correcting for challenging confounding factors

U ni ve rs ity o f C al ifo rn ia , S an D ie go , C A . Hepatic steatosis, the intracellular accumulation of triglycerides (triglyceride fat) in hepatocytes, is a common and often asymptomatic condition. An estimated 20 to 80 million Americans have nonalcoholic fatty liver disease (NAFld), which is the most common chronic liver disease in the united States.1 Steatosis is now recognized to play...

Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies

MOTIVATION A common difficulty in large-scale microarray studies is the presence of confounding factors, which may significantly skew estimates of statistical significance, cause unreliable feature selection and high false negative rates. To deal with these difficulties, an algorithmic framework known as Surrogate Variable Analysis (SVA) was recently proposed. RESULTS Based on the notion that...

Surrogate Measures of Safety

Operating theatre modelling: integrating social measures

Hospital resource modelling literature is primarily focussed on productivity and efficiency measures. In this paper, our focus is on the alignment of the most valuable revenue factor, the operating room (OR) with the most valuable cost factor, the staff. When aligning these economic and social decisions, respectively, into one sustainable model, simulation results justify the integration of the...